HPV, or human papillomavirus, is a very common virus. Most sexually active people—about 70 percent—will have an HPV infection at some point in their lives. Most commonly known is the link between HPV and cervical cancer in women. However, men are also at risk for developing HPV-related cancers. So even though HPV-related cancer is rare overall, it's important for men to understand their risk for HPV and learn how to protect themselves.